Clinical, magnetic resonance imaging, and histological description of a choroid plexus papilloma with disseminated intraventricular and spinal cerebrospinal fluid drop metastases in a young adult dog: a case report

Clinical, magnetic resonance imaging, and histological description of a choroid plexus papilloma with disseminated intraventricular and spinal cerebrospinal fluid drop metastases in a young adult dog: a case report

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A 2-year-old male entire Cane Corso was presented for Doors investigations into a 1-week history of ambulatory paraparesis and pelvic limb ataxia gradually deteriorating.Magnetic resonance imaging (MRI) revealed intraventricular space-occupying lesions affecting the fourth ventricle and lateral apertures and intradural-extramedullary space-occupying lesions at the level of C7 vertebra, L4-L5, and L7-S1 intervertebral disk spaces.Due to poor quality of life, the patient was euthanized.A post-mortem examination revealed partially encapsulated, multifocally infiltrative, and moderately cellular neoplastic masses.

The histological description was similar for all masses.The cells appeared cuboidal with round Girls Sneakers central nuclei and a moderate amount of eosinophilic cytoplasm and were arranged almost exclusively in single-layered papilliform patterns supported by a fibrovascular stroma.Mitoses were rarely observed (1/2.37 mm2).

The primary neoplasm was morphologically most consistent with a choroid plexus papilloma despite drop metastases.This is the first report of a histologically confirmed primary ventricular choroid plexus papilloma causing disseminated MRI-apparent intraventricular and spinal drop metastases.